top of page

Caspase-1/11 Controls Zika Virus Replication in Astrocytes by Regulating Glycolytic Metabolism. preprint

https://doi.org/10.21203/rs.3.rs-4320553/v1

Ingrid S. Farias, Guilherme Ribeiro, Isaú H. Noronha, Jean P. S. Peron, Pedro M. Moraes Vieira, Jose C. Alves-Filho, Karina R. Bortoluci.

Three Main SCFAs Mitigate Lung Inflammation and Tissue Remodeling Nlrp3-Dependent in Murine HDM-Induced Neutrophilic Asthma. Inflammation. 2024

doi: 10.1007/s10753-024-01983-x. 

Tagé BSS, Gonzatti MB, Vieira RP, Keller AC, Bortoluci KR, Aimbire F.  

The impact of inflammatory and metabolic markers on depression, anxiety, and cognition after COVID-19: A narrative review

Trends in Psychiatry and Psychotherapy 2023 | Journal article

DOI: 10.47626/2237-6089-2022-0599

Elton Jorge Bessa Diniz; Fulvio Alexandre Scorza; Fabrício Maués Santos Rodrigues; Claudia Berlim de Mello; Tatiana Carvalho de Souza Bonetti; Karina Ramalho Bortoluci; Jair de Jesus Mari

 

NAIP/NLRC4 inflammasome participates in macrophage responses to Trypanosoma cruzi by a mechanism that relies on cathepsin-dependent caspase-1 cleavage

Frontiers in Immunology 2023-12-06 | Journal article

DOI: 10.3389/fimmu.2023.1282856 Part of ISSN: 1664-3224

Marcelo Pires Amaral; Felipe Daniel Cardoso; Ingrid Sancho de Farias; Rafael Queiroz de Souza; Kely Catarine Matteucci; Ana Claudia Torrecilhas; Karina Ramalho Bortoluci

 

Lysicamine Reduces Protein Kinase B (AKT) Activation and Promotes Necrosis in Anaplastic Thyroid Cancer

Pharmaceuticals 2023-12-04 | Journal article

DOI: 10.3390/ph16121687 Part of ISSN: 1424-8247

Mariana Teixeira Rodrigues; Ana Paula Picaro Michelli; Gustavo Felisola Caso; Paloma Ramos de Oliveira; Rodrigues-Junior, DM; Mirian Galliote Morale; Joel Machado Júnior; Karina Ramalho Bortoluci; rodrigo tamura; Tamiris Reissa Cipriano da Silva et al.

 

Lysosomal cathepsins act in concert with Gasdermin-D during NAIP/NLRC4-dependent IL-1β secretion

Cell Death & Disease 2022-12-08 | Journal article

DOI: 10.1038/s41419-022-05476-3

Laura Migliari Branco; Marcelo Pires Amaral; Henning Boekhoff; Ana Beatriz Figueiredo de Lima; Ingrid Sancho Farias; Silvia Lucena Lage; Gustavo José Silva Pereira; Bernardo Simões Franklin; Karina Ramalho Bortoluci

 

Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi <i>In Vitro</i> and <i>In Vivo</i>

Antimicrobial Agents and Chemotherapy 2022-11-15 | Journal article

DOI: 10.1128/aac.00284-22 Part of ISSN: 0066-4804 Part of ISSN: 1098-6596

Ramendra P. Pandey; Marilda Savoia Nascimento; Caio Haddad Franco; Karina Bortoluci; Marcelo Nunes Silva; Bianca Zingales; Daniel Gibaldi; Leda Castaño Barrios; Joseli Lannes-Vieira; Leonardo Moro Cariste et al.

 

Extracellular vesicles derived from head and neck squamous cells carcinoma inhibit NLRP3 inflammasomes

Current Research in Immunology 2021 | Journal article

DOI: 10.1016/j.crimmu.2021.10.005

Luiza Zainotti Miguel Fahur Bottino; Dorival Mendes Rodrigues-Junior; Ingrid Sancho de Farias; Laura Migliari Branco; N. Gopalakrishna Iyer; Gabriela Estrela de Albuquerque; André Luiz Vettore; Karina Ramalho Bortoluci

 

Absence of Bim sensitizes mice to experimental Trypanosoma cruzi infection

Cell Death & Disease 2021-07-10 | Journal article

DOI: 10.1038/s41419-021-03964-6

Marcela Hernández-Torres; Rogério Silva do Nascimento; Monica Cardozo Rebouças; Alexandra Cassado; Kely Catarine Matteucci; Maria Regina D’Império-Lima; José Ronnie C. Vasconcelos; Karina R. Bortoluci; José Maria Alvarez; Gustavo P. Amarante-Mendes

 

Rapamycin Improves the Response of Effector and Memory CD8+ T Cells Induced by Immunization With ASP2 of Trypanosoma cruzi

Frontiers in Cellular and Infection Microbiology 2021-05-25 | Journal article

DOI: 10.3389/fcimb.2021.676183 Part of ISSN: 2235-2988

Moraschi, B.F., Noronha, I.H., Ferreira, C.P., ...Bortoluci, K.R., Vasconcelos, J.R.C.

 

Inflammatory effect of Bothropstoxin-I from Bothrops jararacussu venom mediated by NLRP3 inflammasome involves ATP and P2X7 receptor

Clinical Science 2021-03-12 | Journal article

DOI: 10.1042/cs20201419 Part of ISSN: 0143-5221 Part of ISSN: 1470-8736

Ranéia e Silva, P.A., De Lima, D.S., Luiz, J.P.M., ...Bortoluci, K.R., Faquim-Mauro, E.L.

 

Role of Annexin A1 in NLRP3 Inflammasome Activation in Murine Neutrophils

Cells 2021-01-11 | Journal article

DOI: 10.3390/cells10010121 Part of ISSN: 2073-4409

José Marcos Sanches, Rebeca Correia-Silva, Gustavo Henrique Bueno Duarte, Anna Maria Fernandes, Salvador Sanchez-Vinces, Patricia O. Carvalho, Sonia Maria Oliani, Karina Ramalho Bortoluci, Vanessa Moreira, Cristiane Damas Gil.

 

The global response to the COVID-19 pandemic: how have immunology societies contributed?

Nature Reviews Immunology 2020-10-10 | Journal article

DOI: 10.1038/s41577-020-00428-4

Faith Osier; Jenny P. Y. Ting; John Fraser; Bart N. Lambrecht; Marta Romano; Ricardo T. Gazzinelli; Karina R. Bortoluci; Dario S. Zamboni; Arne N. Akbar; Jennie Evans et al.

 

Caspase-8 and FADD: Where Cell Death and Inflammation Collide

Immunity 2020-06 | Journal article

DOI: 10.1016/j.immuni.2020.05.008 Part of ISSN: 1074-7613

Marcelo Pires Amaral, Karina Ramalho Bortoluci

 

CXCR3 chemokine receptor contributes to specific CD8+ T cell activation by pDC during infection with intracellular pathogens

PLOS Neglected Tropical Diseases 2020-06-23 | Journal article

DOI: 10.1371/journal.pntd.0008414 Part of ISSN: 1935-2735

Camila Pontes Ferreira, Leonardo de Moro Cariste, Isaú Henrique Noronha, Danielle Fernandes Durso, Joseli Lannes-Vieira, Karina Ramalho Bortoluci, Daniel Araki Ribeiro, Douglas Golenbock, Ricardo Tostes Gazzinelli, José Ronnie Carvalho de Vasconcelos.

 

Paradise revealed III: why so many ways to die? Apoptosis, necroptosis, pyroptosis, and beyond

Cell Death & Differentiation 2020-05 | Journal article

DOI: 10.1038/s41418-020-0526-z

Marcelo Pires Amaral; Laura Migliari Branco; Andreas Strasser; Vishva M. Dixit; Karina Ramalho Bortoluci

 

Annexin A1 Regulates NLRP3 Inflammasome Activation and Modifies Lipid Release Profile in Isolated Peritoneal Macrophages

Cells 2020-04-09 | Journal article

DOI: 10.3390/cells9040926

José Marcos Sanches; Laura Migliari Branco; Gustavo Henrique Bueno Duarte; Sonia Maria Oliani; Karina Ramalho Bortoluci; Vanessa Moreira; Cristiane Damas Gil

 

RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes

Frontiers in Immunology 2020-04-09 | Journal article

DOI: 10.3389/fimmu.2020.00536 Part of ISSN: 1664-3224

Rana A, De Almeida FC, Paico Montero HA, Gonzales C, Maryanne M, Bortoluci KR, Sad S, Amarante-Mendes, GP.

 

Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes

Science Advances 2020-03 | Journal article

DOI: 10.1126/sciadv.aax6346 Part of ISSN: 2375-2548

Reis A, Barboza R, Murillo O, Barateiro A, Peixoto EPM, Lima FA, Gomes VM, Dombrowski J, Leal VNC, Araujo F, Bandeira CL, Araujo RBD, Neres R, Souza RM, Costa F, Pontillo A, Bevilacqua E, Wrenger C, Wunderlich G, Palmisano G, Labriola L, Bortoluci KR, Gonçalves CP, Goncalves L, Epiphanio S et al. Marinho CRF.

 

Concomitant Isolation of Primary Astrocytes and Microglia for Protozoa Parasite Infection

Journal of Visualized Experiments 2020-03-18 | Journal article

DOI: 10.3791/60680 Part of ISSN: 1940-087X

Pacheco AL, Amaral MO, De Farias IS, Bottino LZMF, Bortoluci KR.

 

Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2

The Journal of Experimental Medicine 2020-03-02 | Journal article

DOI: 10.1084/jem.20190489 Part of ISSN: 0022-1007 Part of ISSN: 1540-9538

Fachi JL; Rodrigues PB; Sécca C; Mato FCP; Luccia BD; Felipe JS; Pral LP; Rungue M; Rocha VM; Sato FT; Sampaio U; Clerici MTPS; Rodrigues HG; Camara, NO; Consonni SR; Vieira, AT; Oliveira, SC.; Mackay CR; Layden BT; Bortoluci, KR; Colonna M; Vinolo MA.

 

Frontline Science: Autophagy is a cell autonomous effector mechanism mediated by NLRP3 to control Trypanosoma cruzi infection

2019-05-09 | Journal article

DOI: 10.1002/jlb.hi1118-461r Part of ISSN: 0741-5400 Part of ISSN: 1938-3673

Matteucci K, Pereira GJS, Weinlich R, Bortoluci KR.

 

The impairment in the NLRP3‐induced NO secretion renders astrocytes highly permissive to T. cruzi replication

2019-04-18 | Journal article DOI: 10.1002/jlb.4ab1118-416rr

Part of ISSN: 0741-5400 Part of ISSN: 1938-3673

Pacheco AL, Vicentini G, Matteucci KC, Ribeiro RR, Weinlich R, Bortoluci KR.

 

OIP5 Expression Sensitize Glioblastoma Cells to Lomustine Treatment

Journal of Molecular Neuroscience 2018 | Journal article

DOI: 10.1007/s12031-018-1184-1

Rodrigues-Junior, D.M.; Biassi, T.P.; Carlin, V.; Buri, M.V.; Torrecilhas, A.C.; Bortoluci, K.R.; Vettore, A.L.

 

Pattern recognition receptors and the host cell death molecular machinery

Frontiers in Immunology 2018 | Journal article

DOI: 10.3389/fimmu.2018.02379

Amarante-Mendes, G.P.; Adjemian, S.; Branco, L.M.; Zanetti, L.C.; Weinlich, R.; Bortoluci, K.R.

 

Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage

Scientific Reports 2017 | Journal article

DOI: 10.1038/srep41686 http://www.nature.com/articles/srep41686#supplementary-information

Buzzo, Carina de Lima; Medina, Tiago; Branco, Laura M.; Lage, Silvia L.; Ferreira, Luís Carlos de Souza; Amarante-Mendes, Gustavo P.; Hottiger, Michael O.; De Carvalho, Daniel D.; Bortoluci, Karina R.

 

A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells

PLoS Pathog 2016 | Journal article

DOI: 10.1371/journal.ppat.1005698

Ersching, J.; Basso, A. S.; Kalich, V. L.; Bortoluci, K. R.; Rodrigues, M. M.

 

Endostatin gene therapy inhibits intratumoral macrophage M2 polarization

Biomed Pharmacother 2016 | Journal article

DOI: 10.1016/j.biopha.2016.01.035

Foguer, K.; Braga, M.e S; Peron, J. P.; Bortoluci, K. R.; Bellini, M. H.

 

Revisiting mouse peritoneal macrophages: heterogeneity, development, and function

Front Immunol 2015 | Journal article

DOI: 10.3389/fimmu.2015.00225

Cassado, A.os A; D'Império Lima, M. R.; Bortoluci, K. R.

 

Chagas Disease: Still Many Unsolved Issues

Mediators Inflamm 2014 | Journal article

DOI: 10.1155/2014/912965

Alvarez, J. M.; Fonseca, R.; Borges da Silva, H.; Marinho, C. R.; Bortoluci, K. R.; Sardinha, L. R.; Epiphanio, S.; D'Império Lima, M. R.

 

Emerging Concepts about NAIP/NLRC4 Inflammasomes

Front Immunol 2014 | Journal article

DOI: 10.3389/fimmu.2014.00309

Lage, S. L.; Longo, C.; Branco, L. M.; da Costa, T. B.; Buzzo, C.e L; Bortoluci, K. R.

 

Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis

PLoS Pathog 2014 | Journal article

DOI: 10.1371/journal.ppat.1004188

Amaral, E. P.; Ribeiro, S. C.; Lanes, V. R.; Almeida, F. M.; de Andrade, M. R.; Bomfim, C. C.; Salles, E. M.; Bortoluci, K. R.; Coutinho-Silva, R.; Hirata, M. H. et al.

 

Critical Role of ASC Inflammasomes and Bacterial Type IV Secretion System in Caspase-1 Activation and Host Innate Resistance to Brucella abortus Infection

Journal of Immunology 2013 | Journal article

DOI: 10.4049/jimmunol.1202817

Gomes, Marco Tulio R.; Campos, Priscila C.; Oliveira, Fernanda S.; Corsetti, Patricia P.; Bortoluci, Karina R.; Cunha, Larissa D.; Zamboni, Dario S.; Oliveira, Sergio C.

 

Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses

Proceedings of the National Academy of Sciences of the United States of America

2013 | Journal article

DOI: 10.1073/pnas.1305316110

Lage, Silvia L.; Buzzo, Carina L.; Amaral, Eduardo P.; Matteucci, Kely C.; Massis, Liliana M.; Icimoto, Marcelo Y.; Carmona, Adriana Karaoglanovic; D'Imperio Lima, Maria R.; Rodrigues, Mauricio M.; Ferreira, Luis C. S. et al.

 

Evaluation of pyroptosis in macrophages using cytosolic delivery of purified flagellin

Methods 2013 | Journal article

DOI: 10.1016/j.ymeth.2013.02.010

Lage, Silvia L.; Amarante-Mendes, Gustavo P.; Bortoluci, Karina R.

 

Inflammasome-derived IL-1 beta production induces nitric oxide-mediated resistance to Leishmania

Nature Medicine 2013 | Journal article

DOI: 10.1038/nm.3221

Lima-Junior, Djalma S.; Costa, Diego L.; Carregaro, Vanessa; Cunha, Larissa D.; Silva, Alexandre L. N.; Mineo, Tiago W. P.; Gutierrez, Fredy R. S.; Bellio, Maria; Bortoluci, Karina R.; Flavell, Richard A. et al.

 

NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production

PLoS Negl Trop Dis 2013 | Journal article

DOI: 10.1371/journal.pntd.0002469

Gonçalves, V. M.; Matteucci, K. C.; Buzzo, C. L.; Miollo, B. H.; Ferrante, D.; Torrecilhas, A. C.; Rodrigues, M. M.; Alvarez, J. M.; Bortoluci, K. R.

 

Anti-IL-2 Treatment Impairs the Expansion of T-reg Cell Population during Acute Malaria and Enhances the Th1 Cell Response at the Chronic Disease

Plos One 2012 | Journal article

DOI: 10.1371/journal.pone.0029894

Zago, Claudia A.; Bortoluci, Karina R.; Sardinha, Luiz R.; Pretel, Fernando D.; Castillo-Mendez, Sheyla I.; Freitas do Rosario, Ana Paula; Hiyane, Meire I.; Muxel, Sandra M.; Rodriguez-Malaga, Sergio M.; Abrahamsohn, Ises A. et al.

 

Guidelines for the use and interpretation of assays for monitoring autophagy

Autophagy 2012 | Journal article

DOI: 10.4161/auto.19496

Klionsky, Daniel J.; Abdalla, Fabio C.; Abeliovich, Hagai; Abraham, Robert T.; Acevedo-Arozena, Abraham; Adeli, Khosrow; Agholme, Lotta; Agnello, Maria; Agostinis, Patrizia; Aguirre-Ghiso, Julio A. et al.

 

Pathogen-Induced Proapoptotic Phenotype and High CD95 (Fas) Expression Accompany a Suboptimal CD8(+) T-Cell Response: Reversal by Adenoviral Vaccine

Plos Pathogens 2012 | Journal article

DOI: 10.1371/journal.ppat.1002699

Vasconcelos, Jose Ronnie; Bruna-Romero, Oscar; Araujo, Adriano F.; Dominguez, Mariana R.; Ersching, Jonatan; de Alencar, Bruna C. G.; Machado, Alexandre V.; Gazzinelli, Ricardo T.; Bortoluci, Karina R.; Amarante-Mendes, Gustavo P. et al.

 

Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production

Clinical &amp; Developmental Immunology 2012 | Journal article

DOI: 10.1155/2012/721817

Faustino, Lucas; Mucida, Daniel; Keller, Alexandre Castro; Demengeot, Jocelyne; Bortoluci, Karina; Sardinha, Luiz Roberto; Takenaka, Maisa Carla; Basso, Alexandre Salgado; Caetano Faria, Ana Maria; Russo, Momtchilo

 

Role of interplay between IL-4 and IFN-gamma in the in regulating M1 macrophage polarization induced by Nattectin

International Immunopharmacology 2012 | Journal article

DOI: 10.1016/j.intimp.2012.08.009

Ishizuka, Edson Kiyotaka; Ferreira, Marcio Jose; Grund, Lidiane Zito; Martins Coutinho, Erica Maria; Komegae, Evilin Naname; Cassado, Alexandra Anjos; Bortoluci, Karina Ramalho; Lopes-Ferreira, Monica; Lima, Carla

 

Cellular Renewal and Improvement of Local Cell Effector Activity in Peritoneal Cavity in Response to Infectious Stimuli

Plos One 2011 | Journal article

DOI: 10.1371/journal.pone.0022141

Cassado, Alexandra dos Anjos; Tavares de Albuquerque, Jose Antonio; Sardinha, Luiz Roberto; Buzzo, Carina de Lima; Faustino, Lucas; Nascimento, Rogerio; Ghosn, Eliver Eid Bou; D'Imperio Lima, Maria Regina; Mosig Alvarez, Jose Maria; Bortoluci, Karina Ramalho

 

A Novel Pathway for Inducible Nitric-oxide Synthase Activation through Inflammasomes

Journal of Biological Chemistry 2010 | Journal article

DOI: 10.1074/jbc.M110.124297

Buzzo, Carina L.; Campopiano, Julia C.; Massis, Liliana M.; Lage, Silvia L.; Cassado, Alexandra A.; Leme-Souza, Rafael; Cunha, Larissa D.; Russo, Momtchilo; Zamboni, Dario S.; Amarante-Mendes, Gustavo P. et al.

 

Control of infection by pyroptosis and autophagy: role of TLR and NLR

Cellular and Molecular Life Sciences 2010 | Journal article

DOI: 10.1007/s00018-010-0335-5

Bortoluci, Karina R.; Medzhitov, Ruslan

 

Paradise revealed: first-class science rocked by the sound of the waves

Cell Death and Differentiation 2010 | Journal article

DOI: 10.1038/cdd.2010.66

Amarante-Mendes, G. P.; Bortoluci, K. R.; Bozza, P. T.; Chammas, R.; Viola, J. P. B.

 

Two physically, functionally, and developmentally distinct peritoneal macrophage subsets

Proceedings of the National Academy of Sciences of the United States of America

2010 | Journal article

Bou Ghosn, Eliver Eid; Cassado, Alexandra A.; Govoni, Gregory R.; Fukuhara, Takeshi; Yang, Yang; Monack, Denise M.; Bortoluci, Karina R.; Almeida, Sandro R.; Herzenberg, Leonard A.; Herzenberg, Leonore A.

 

Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease

Microbes and Infection 2009 | Journal article

DOI: 10.1016/j.micinf.2009.07.011

Marinho, Claudio R. F.; Nunez-Apaza, Luis N.; Bortoluci, Karina R.; Bombeiro, Andre L.; Bucci, Daniella Z.; Grisotto, Marcos G.; Sardinha, Luiz R.; Jorquera, Christian E.; Lira, Sergio; D'Imperio Lima, Maria Regina et al.

 

TLR4/MYD88-dependent, LPS-induced synthesis of PGE(2) by macrophages or dendritic cells prevents anti-CD3-mediated CD95L upregulation in T cells

Cell Death and Differentiation 2008 | Journal article

DOI: 10.1038/cdd.2008.128

Weinlich, R.; Bortoluci, K. R.; Chehab, C. F.; Serezani, C. H.; Ulbrich, A. G.; Peters-Golden, M.; Russo, M.; Amarante-Mendes, G. P.

 

Toll-like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin-specific allergic airway disease: role of MyD88 adaptor molecule and interleukin-12/interferon-gamma axis

Clinical and Experimental Allergy 2008 | Journal article

DOI: 10.1111/j.1365-2222.2008.03036.x

Bortolatto, J.; Borducchi, E.; Rodriguez, D.; Keller, A. C.; Faquim-Mauro, E.; Bortoluci, K. R.; Mucida, D.; Gomes, E.; Christ, A.; Schnyder-Candrian, S. et al.

 

IFN-gamma, but not nitric oxide or specific IgG, is essential for the in vivo control of low-virulence sylvio X10/4 Trypanosoma cruzi parasites

Scandinavian Journal of Immunology 2007 | Journal article

DOI: 10.1111/j.1365-3083.2007.01958.x

Marinho, C. R. F.; Nunez-Apaza, L. N.; Martins-Santos, R.; Bastos, K. R. B.; Bombeiro, A. L.; Bucci, D. Z.; Sardinha, L. R.; Lima, M. R. D.; Alvarez, J. M.

 

Interaction between Paracoccidioides brasiliensis and pulmonary dendritic cells induces interleukin-10 production and toll-like receptor-2 expression: Possible mechanisms of susceptibility

Journal of Infectious Diseases 2007 | Journal article

DOI: 10.1086/521369

Ferreira, Karen Spadari; Bastos, Karina Ramalho; Russo, Momtchilo; Almeida, Sandro Rogerio

 

Role of endogenous IFN-gamma in macrophage programming induced by IL-12 and IL-18

Journal of Interferon and Cytokine Research 2007 | Journal article

DOI: 10.1089/jir.2007.0128

Bastos, Karina R. B.; Barboza, Renato; Sardinha, Luiz; Russo, Momtchilo; Alvarez, Jose M.; D'Imperio Lima, Maria Regina

 

Role of interferon-gamma during CpG oligodeoxynucleotide-adjuvanted immunization with recombinant proteins

Vaccine 2007 | Journal article

DOI: 10.1016/j.vaccine.2007.05.031

Rosa, Daniela Santoro; Bastos, Karina R.; Bargieri, Daniel Youssef; Tzelepis, Fanny; Nomizo, Auro; Russo, Momtchilo; Soares, Irene S.; Rodrigues, Mauricio M.

Contribution of NKNK T, gamma delta T, and alpha beta T cells to the gamma interferon response required for liver protection against Trypanosoma cruzi

Infection and Immunity 2006 | Journal article

DOI: 10.1128/IAI.74.4.2031-2042.2006

Sardinha, LR; Elias, RM; Mosca, T; Bastos, KRB; Marinho, CRF; Lima, MR; Alvarez, JMM

 

Analysis of the activation profile of dendritic cells derived from the bone marrow of interleukin-12/interleukin-23-deficient mice

Immunology 2005 | Journal article

DOI: 10.1111/j.1365-2567.2005.02118.x

Bastos, KRB; de Moraes, LD; Zago, CA; Marinho, CRF; Russo, M; Alvarez, JMM; Lima, MRD

 

Role of CD28 in polyclonal and specific T and B cell responses required for protection against blood stage malaria

Journal of Immunology 2005 | Journal article

DOI: 10.4049/jimmunol.174.2.790

Elias, R.M.; Sardinha, L.R.; Bastos, K.R.B.; Zago, C.A.; Freitas Da Silva, A.P.; Alvarez, J.M.; Lima, M.R.D.

 

Challenge of Trypanosoma cruzi chronically infected mice with trypomastigotes activates the immune system and reduces subpatent parasitemia levels

Journal of Parasitology 2004 | Journal article

DOI: 10.1645/GE-212R

Marinho, CRF; Bastos, KRB; Sardinha, LR; Grisotto, MG; Lima, MRD; Alvarez, JM

 

Pathology affects different organs in two mouse strains chronically infected by a Trypanosoma cruzi clone: a model for genetic a studies of Chagas' disease

Infection and Immunity 2004 | Journal article

DOI: 10.1128/IAI.72.4.2350-2357.2004

Marinho, CRF; Bucci, DZ; Dagli, MLZ; Bastos, KRB; Grisotto, MG; Sardinha, LR; Baptista, CRGM; Goncalves, CP; Lima, MRD; Alvarez, JM

 

What kind of message does IL-12/IL-23 bring to macrophages and dendritic cells?

Microbes and Infection 2004 | Journal article

DOI: 10.1016/j.micinf.2004.02.012

Bastos, K.R.B.; Marinho, C.R.F.; Barboza, R.; Russo, M.; Álvarez, J.M.; D'Império Lima, M.R.

 

Impaired macrophage responses may contribute to exacerbation of blood-stage Plasmodium chabaudi chabaudi malaria in interleukin-12-deficient mice

Journal of Interferon and Cytokine Research 2002 | Journal article

DOI: 10.1089/10799900260475713

Bastos, K. R. B.; Barboza, R.; Elias, R. M.; Sardinha, L. R.; Grisotto, M. G.; Marinho, C. R. F.; Amarante-Mendes, G. P.; Alvarez, J. M.; Lima, M. R. D.

 

Macrophages from IL-12p40-deficient mice have a bias toward the M2 activation profile

Journal of Leukocyte Biology 2002 | Journal article

Bastos, KRB; Alvarez, JM; Marinho, CRF; Rizzo, LV; Lima, MRD

 

Susceptibility of the different developmental stages of the asexual (schizogonic) erythrocyte cycle of Plasmodium chabaudi chabaudi to hyperimmune serum, immunoglobulin (Ig)G1, IgG2a and F(ab ')2 fragments

Parasite Immunology 2001 | Journal article

DOI: 10.1046/j.1365-3024.2001.00419.x

Cavinato, RA; Bastos, KRB; Sardinha, LR; Elias, RM; Alvarez, JM; Lima, MRD

PUBLICATIONS

bottom of page